Ah, some dust which matches my setup.
I do the following
1). open cpu, u did that already, remove power, take out GPU
2). use some cloth, or soft plastic to prevent fan from moving,
Use vacuum cleaner, first suction mode, then blower mode to remove the dust
do not use vacuum cleaner more than a minute or two, as air would get hot once VC motor get hot.
3). move fan by hand and using ear cleaning buds(Doesn't needs to be Johnsons one he he he) clean the tips of the fan blades.
4). insert it back into system and make sure to fasten the screws.
Another advanced option to drastically improve performance would need heat-sink compound (usually comes in syringe)
unscrew the housing of GPU Card then find out which screws are holding the heat-sink to the GPU, unscrew then, now you have fan and heat-sink in your hand and card separately,
Clean it in details, and most important, remove existing heat-sink compound from GPU, clean surface with soft cloth, NO WATER or solvent should be used, re-apply fresh heat-sink compound and re-assemble the heat-sink fins and fan.
double check all the screws are fastened and re-insert the card.